● Hopenta-Empowers Progress, Builds Hope
NEURODEVLOPMENTAL SUPPORT FOR CHILDREN
Hopenta contains Hopantenic acid, a selective presynaptic - partial GABA BRI agonist that helps to improve comprehension, cognition, speech, attention and calmness.
Supports Neurodevelopment
Used in ADHD, ASD, Epilepsy & More
Safe & Well Tolerated
The Trust Layer
Why Early Brain Support Matters
The early years are decisive for a child's lifelong learning and development.
Recognising the signs early — and supporting them — can change the
trajectory of a child's future.
Language/Speech
Supports the development of both impressive & expressive speech
Cognition
Supports the regulation children need to engage, sit with a task and learn.
Motor Function
Supports movement control by balancing excitation and inhibition.
Social Skills
Supports the calm, regulated state from which social connection grows.
All About Hopenta · Product Science
What is Hopenta?
Hopenta contains Hopantenic Acid — a homologue of pantothenic acid that supports language,cognition, motor and social skills.
ACTIVE INGREDIENTS
Hopantenic Acid
60 mg/ml
Mechanism of Action (MOA)
• A homologue of pantothenic acid.
• Facilitates passage through the blood– brain barrier - lipophilic in nature.
• Binds weakly to the GABA-B R1 subunit but does not completely activate R2 — a Presynaptic Partial GABA-B Agonist.
• Maintains a balance between inhibition and excitation — useful for cognitive, speech, motor and social function.
All About Hopenta · Product Science
What is Hopenta?
Hopenta contains Hopantenic Acid — a homologue of pantothenic acid that supports language,cognition, motor and social skills.
ACTIVE INGREDIENTS
Hopantenic Acid
60 mg/ml
Mechanism of Action (MOA)
• A homologue of pantothenic acid.
• Facilitates passage through the blood– brain barrier - lipophilic in nature.
• Binds weakly to the GABA-B R1 subunit but does not completely activate R2 — a Presynaptic Partial GABA-B Agonist.
• Maintains a balance between inhibition and excitation — useful for cognitive, speech, motor and social function.
How it Works
From receptor to real-world milestones
HOPENTA binds R1 but does not fully activate R2 — partial agonism that helps avoid the dizziness and sedation seen with full GABA-B activation.
Neurodevelopmental Milestones
The Science
What is LTP?
A persistent strengthening of synapses
Long-Term Potentiation leads to a long-lasting increase in signal transmission between neurons — a key mechanism for learning and memory.
LTP
It is a fundamental mechanism for learning, memory formation and improved cognition.
In short
By modulating LTP, Hopenta supports synaptic strengthening that turns therapy and daily practice into long lasting developmental gains.
Developmental Milestones
How LTP acts on developmental milestones
Indication
For neurodevelopmental delay management
Used in the management of neurodevelopmental delay and associated disorders.
ADHD
ASD
Epilepsy
Dyslexia
Cerebral Palsy
Tics
Developmental Language Disorder
Hyperkinetic Behaviour Disorder
Hypoxic-Ischemic Brain Injury
Dosage
30 mg/Kg/day, in divided doses
Recommended for children 6 months and above, under medical supervision.
| BODY WEIGHT (kg) | DOSAGE (mg/day) | HOPENTA DOSE |
|---|---|---|
| 10 | 300 | 2.5 ml BID |
| 15 | 450 | 3.5 ml BID |
| 20 | 600 | 5 ml BID |
| 25 | 750 | 6 ml BID |
| 30 | 900 | 7.5 ml BID |
DOSAGE
30 mg/kg/day
in divided doses
RECOMMENDED AGE
6 months +
under supervision
Interaction with other medicine: Prolongs the effect of barbiturates, enhances the effects of anticonvulsants, and prevents side effects of phenobarbital, carbamazepine and neuroleptics.
Local anaesthetics: The medicine potentiates the action of local anaesthetics (procaine).
Improve LCMS Outcomes
Hopenta stabilizes neuronal excitability & improve skills
