Resources

Summary table

Condition Age Group Patient Population Dosage Duration Results
Hypoxic ischemic brain injury Premature infants aged 6–12 months 87 patients
(44 standard + Hopantenic acid,
43 standard + placebo)
Hopantenic acid syrup (100 mg/ml),
2× a day, 30–50 mg/kg/day.
2 months
  • Improvement in personal and social domains
  • Improved manipulation with objects
  • Improved motor activity
  • Improved hearing and speech
  • Improved visual-motor coordination
Cerebral Palsy with cognitive impairment Children & adolescents aged 8–14 years 100 patients
(50 Hopantenic acid + basic therapy,
50 basic therapy only)
Hopantenic acid 1000–1500 mg/day
(30–50 mg/kg), oral, 2×/day.
3 months
  • Visual memory
  • Verbal memory
ADHD Children aged 6–12 years 100 patients
(50 Hopantenic acid, 50 placebo;
89 completed)
Hopantenic acid tablets 250 mg,
30 mg/kg/day, 2×/day.
4 months WFIRS-P scale:
  • Family
  • School and learning
  • Child’s self-concept
  • Risky activities
Epilepsy with cognitive impairment Children aged 4–7 years 63 patients
(40 Hopantenic acid, 23 control)
Hopantenic acid
20–30 mg/kg/day
2 months
  • Visual and verbal memory
  • Seizure frequency decreased by 72.1% in the Hopantenic acid group versus 16.7% with placebo
Tic disorders Children aged 10–17 years 43 patients (Hopantenic acid),
20 healthy controls
Hopantenic acid 500 mg,
3×/day
6 weeks
  • Reduced total tic severity
  • Situational anxiety decreased
  • Short-term auditory-verbal memory volume increased
Affective-respiratory paroxysms
(breath-holding spells)
Children aged 2–4 years 60 patients
(30 Hopantenic acid,
30 psychological therapy only)
Hopantenic acid syrup 100 mg/ml,
30–35 mg/kg/day
3 months
  • Clinical improvement was observed in 73.3% of patients in the Hopantenic acid group compared with 16.7% in the comparison group
  • Anxiety reduced

PUBLICATION

Explore the research and review publications on hopantenic acid
in pediatric neurological and developmental disorders.

Meta Analysis

Efficacy and Safety of Hopantenic Acid inPediatric Neurological and
DevelopmentalDisorders: A Systematic Review and Meta-Analysis

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Attention-Deficit/Hyperactivity Disorder(ADHD)

Pharmacotherapy of Attention Deficit Hyperactivity Disorder in Children: Results of a Multicenter, Double-Blind, Placebo-Controlled Trial of Hopantenic Acid

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HYPOXIC

Pharmacotherapy of psychomotor developmental delay in children aged 6-12 months, born prematurely and having suffered hypoxic-ischemic brain injury (double-blind comparative multicenter study) placebo-controlled study

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Epilepsy

Diagnosis and correction of cognitive impairment in preschool children with epilepsy


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Cerebral Palsy

Hopantenic Acid and Cognitive Function in Children With Cerebral Palsy

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TICS

METHODS OF OBJECTIVE CONTROL OF THERAPY EFFECTIVENESS In children with TICS


Affective- Respirtatory

Use of the drug pantogam syrup in the treatment of affective-respiratory paroxysms in young children

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Meta Analysis

Efficacy and Safety of Hopantenic Acid inPediatric Neurological and
DevelopmentalDisorders: A Systematic Review and Meta-Analysis

🗎 Download Pdf

Attention-Deficit/Hyperactivity Disorder(ADHD)

Pharmacotherapy of Attention Deficit Hyperactivity Disorder in Children: Results of a Multicenter, Double-Blind, Placebo-Controlled Trial of Hopantenic Acid

🗎 Download Pdf

HYPOXIC

Pharmacotherapy of psychomotor developmental delay in children aged 6-12 months, born prematurely and having suffered hypoxic-ischemic brain injury (double-blind comparative multicenter study) placebo-controlled study

🗎 Download Pdf

Epilepsy

Diagnosis and correction of cognitive impairment in preschool children with epilepsy


🗎 Download Pdf

Cerebral Palsy

Hopantenic Acid and Cognitive Function in Children With Cerebral Palsy

🗎 Download Pdf

TICS

METHODS OF OBJECTIVE CONTROL OF THERAPY EFFECTIVENESS In children with TICS


Affective- Respirtatory

Use of the drug pantogam syrup in the treatment of affective-respiratory paroxysms in young children

🗎 Download Pdf

This is a title

Type your paragraph here

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